Genetics

Three MS studies make the choice of comparison visible. Hedström and colleagues find occupational petroleum lubricant exposure raising MS odds to 1.38 in 2,872 Swedish cases, with an attributable proportion of 0.32 against absence of HLA-A*02:01 and a highest-risk cell of 33.65 resting on 16 cases. Barrantes-Cepas and colleagues score atrophy in 2,187 people against controls and test four mechanisms against ten thousand permuted maps, finding connectivity significant and the gene expression map not. Brownbill and colleagues find the internal reference metabolite itself moving.