Genetics

Natalizumab is best known for keeping immune cells out of the brain in multiple sclerosis—but what happens to those cells left behind in the blood? This blog post explores new research showing how the drug not only blocks immune cell entry into the CNS but subtly reshapes their behavior and balance in the bloodstream. From increased memory T-cells to a quiet dialing down of activation signals, the findings reveal a deeper immunological story behind this powerful MS therapy.