Genetics

This blog post examines the Mendelian randomization study by Vandebergh, Dubois, and Goris, which investigates whether serum 25-hydroxyvitamin D levels and body mass index causally influence multiple sclerosis risk and relapse hazard. The article highlights that genetically predicted higher vitamin D levels are associated with reduced multiple sclerosis susceptibility and lower relapse hazard after disease onset, whereas higher body mass index increases disease risk but does not show clear evidence of affecting relapse occurrence.