Genetics

This blog post discusses the scientific and ethical importance of expanding multiple sclerosis genetics research beyond populations of European ancestry. It explains how multi-ancestry studies can improve understanding of global disease epidemiology, refine the role of the major histocompatibility complex, support cross-ancestral fine mapping, identify novel risk loci, and improve polygenic risk prediction. The post also highlights how inclusive genomic research may clarify differences in disease severity and progression while helping to ensure that future advances in precision medicine benefit people with multiple sclerosis from all ancestral backgrounds.