Genetics

The article "Towards a Global View of Multiple Sclerosis Genetics" by Benjamin Meir Jacobs et al. emphasizes the need for greater diversity in MS genetic research. It highlights how the majority of genome-wide association studies (GWAS) have focused on individuals of European ancestry, leaving non-European populations significantly underrepresented. This imbalance not only limits scientific understanding but also risks perpetuating health disparities, as findings from European studies may not apply to other populations. By broadening MS genetic studies to include more diverse ancestries, researchers could uncover novel risk factors, improve disease prediction, and refine polygenic risk scores, ultimately benefiting all MS patients.