Genetics

This blog post examines a recent study exploring the genetic basis of multiple sclerosis in individuals of South Asian and African ancestry living in the United Kingdom. It highlights how the research confirms the central role of the major histocompatibility complex in MS susceptibility across populations, while also showing that genetic risk scores developed in European cohorts do not transfer equally well to other ancestral groups. The article underscores the scientific and clinical importance of expanding genomic research beyond European ancestry to improve biological insight, fine-mapping of causal variants, and equity in precision medicine.