Genetics
HLA Allele, Four Measures of MS Severity27, Sep 2026
Topic hub
Bioinformatics Tutorials
This page collects hands-on bioinformatics tutorials and workflow notes so technical readers can move from concept to implementation faster.
Core Questions
Which workflows can be made reproducible and reusable?
How can Python, R, and notebooks support genetics and omics analysis?
Which practical tutorials are useful for readers moving from biology to computation?
Topic Clusters
Core Articles
Genetics
Two Loci for How MS Progresses, Not Whether It Starts
23, Sep 2026This post covers Loomis and colleagues' 2023 Scientific Reports study, the first GWAS meta-analysis of longitudinal brain MRI measures of MS...
Genetics
Narrowing 1,091 Metabolites Down to One Enzyme in MS
23, Sep 2026This post covers Noroozi and colleagues' 2026 medRxiv preprint, a layered Mendelian randomization study testing 1,091 plasma metabolites and 309...
Genetics
A MAP1B Variant Tracks With Progressive MS in Women
21, Sep 2026This post covers Djuric and colleagues' 2025 study in International Journal of Molecular Sciences, which tested seven regulatory gene variants...
Genetics
Two Approaches to Iron in MS
20, Sep 2026This post covers Tang and colleagues' 2024 study in Frontiers in Immunology, which pairs a bioinformatics analysis of iron metabolism genes in MS...
Genetics
Checking 4,142 MS Clinical Records Against a Research Cohort
19, Sep 2026This post covers Damotte, Lizee and colleagues' study in Multiple Sclerosis Journal, which identified 4,142 MS patients in the UCSF electronic...
Genetics
Where MS Genetics and Vitamin D Converge on One Enzyme Step
17, Sep 2026This post covers Grigorian and colleagues' 2012 review in Seminars in Immunopathology, arguing that genetic variants in IL7RA, IL2RA, MGAT1 and...
Genetics
A STAT3 Variant Marks White Matter Before MS Begins
12, Sep 2026This post covers the Nature Genetics version of Zeng, Khan and colleagues' multi-ancestry MS GWAS, focusing on what the peer-reviewed version adds...
Genetics
An Iron-Responsive MS Subtype, Proposed From Two Children
12, Sep 2026This post covers van Rensburg and colleagues' 2019 report in Molecular Genetics and Metabolism Reports, a whole exome sequencing study of two boys...
Genetics
Reduced FADS1 Activity and How Severe MS Becomes
11, Sep 2026This post covers Noroozi and colleagues' 2026 medRxiv preprint using layered Mendelian randomization to link lipid metabolism to multiple...
Genetics
MS Genetic Risk, Healthy Brains, and an Effect Measured in Milliseconds
07, Sep 2026This post covers Feng and colleagues' 2026 study in Magnetic Resonance in Medical Sciences, which tested whether a polygenic risk score for...
Genetics
From Metabolite Signature to Drug Target: Glycolysis in Relapsing-Remitting MS
03, Sep 2026This post covers Zahoor and colleagues' 2022 PNAS study, which takes serum metabolomics in treatment-naive relapsing-remitting MS patients through...
Genetics
A Blood Test for Progressive MS? What the Metabolite Signature Actually Shows
02, Sep 2026This post covers Oppong and colleagues' 2024 iScience study using serum NMR metabolomics and whole blood transcriptomics to separate...