Genetics
The Metabolic Switch in Progressive MS, and How Much of It Is Tested06, Sep 2026
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Genetics
The Metabolic Switch in Progressive MS, and How Much of It Is Tested
06, Sep 2026This post takes the mechanistic half of Oppong and colleagues' 2024 iScience study, the whole blood transcriptomics and the gene-metabolite...
Genetics
From Metabolite Signature to Drug Target: Glycolysis in Relapsing-Remitting MS
03, Sep 2026This post covers Zahoor and colleagues' 2022 PNAS study, which takes serum metabolomics in treatment-naive relapsing-remitting MS patients through...
Genetics
A Blood Test for Progressive MS? What the Metabolite Signature Actually Shows
02, Sep 2026This post covers Oppong and colleagues' 2024 iScience study using serum NMR metabolomics and whole blood transcriptomics to separate...
Genetics
Metabolism as Medicine: A New Therapeutic Direction for Multiple Sclerosis
01, Sep 2026This post covers Badawi and colleagues' 2026 Inflammopharmacology review on immunometabolic reprogramming in multiple sclerosis. It walks through...
Genetics
Twelve Genes, Twenty Years, No Answer: Vitamin D and Genetic Susceptibility to MS
31, Aug 2026This post covers a 2021 Biochemical Genetics review by Scazzone and colleagues on SNPs in 12 vitamin D pathway genes and multiple sclerosis...
Genetics
Metabolites and Multiple Sclerosis: What Genetic Studies Agree and Disagree On
30, Aug 2026This post compares four Mendelian randomization studies (2023-2025) testing whether circulating and vitamin D metabolites causally affect multiple...
Genetics
Decoding Multiple Sclerosis Progression Through Blood Metabolomics and Transcriptomics
28, Aug 2026This blog post examines a 2024 iScience study investigating how blood-based metabolomic and transcriptomic signatures may distinguish...
Genetics
How Lipid Metabolism May Shape Multiple Sclerosis Severity: Genetic Evidence from Mendelian Randomization
25, Aug 2026A recent genetic study investigates whether metabolic changes observed in multiple sclerosis (MS) may actively contribute to disease severity...
Genetics
Metabolic Signatures of Multiple Sclerosis: Uncovering Molecular Clues Through Multi-Omic Analysis
24, Aug 2026This blog post examines the study “Metabolome-based signature of disease pathology in MS,” which explores how changes in circulating metabolites...
Genetics
Cerebrospinal Fluid Metabolites and Multiple Sclerosis: Genetic Clues to Disease Risk
22, Aug 2026This blog post examines a recent two-sample Mendelian randomization study investigating whether cerebrospinal fluid metabolites may have causal...
Genetics
How Human Metabolites May Influence Multiple Sclerosis Through HLA Binding
21, Aug 2026This blog post explores research showing how naturally occurring human metabolites may interact with the multiple-sclerosis-associated...
Genetics
Metabolic Signatures of Multiple Sclerosis: What Multi-Omics Reveals About Disease Biology
19, Aug 2026This blog post examines a scientific study that identified a distinctive serum metabolic profile associated with multiple sclerosis (MS). Using a...