Genetics
A Gene, an Exposure, and an Intervention in MS Metabolism17, Oct 2026
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Bioinformatics Tutorials
This page collects hands-on bioinformatics tutorials and workflow notes so technical readers can move from concept to implementation faster.
Core Questions
Which workflows can be made reproducible and reusable?
How can Python, R, and notebooks support genetics and omics analysis?
Which practical tutorials are useful for readers moving from biology to computation?
Topic Clusters
Core Articles
Genetics
Where the Vitamin D Benefit Stops in MS Risk
15, Oct 2026This post covers Yu and colleagues' 2024 Nutrition Journal study, which stacked four layers of evidence on vitamin D and MS: a prospective cohort...
Genetics
Which Metabolites Cause MS? The First Metabolome-Wide Mendelian Randomization Study in MS
12, Oct 2026This post covers Ge and colleagues' 2023 metabolome-wide Mendelian randomization study in the Journal of Neuroimmunology, which tested 571...
Genetics
More Enzyme, Less Branching, and More MS Risk
11, Oct 2026This post covers Mkhikian and colleagues' 2011 Nature Communications study, which inverted the usual order of genetic work by screening...
Genetics
Multiancestry MS GWAS Meets Single-Cell and Spatial Data
11, Oct 2026This post covers Fujimoto and colleagues' 2026 Nature Genetics study, the first MS GWAS in an East Asian population and a four-population...
Genetics
From an MS GWAS Locus to the Gene It Acts Through
08, Oct 2026This post covers the variant-to-gene half of Upcott and colleagues' 2026 medRxiv preprint, which paired the MS susceptibility GWAS with blood and...
Genetics
Single-Nucleus Profiles and Lesion Geography in the MS Cortex
08, Oct 2026This post covers Schirmer and colleagues' 2019 Nature study, which applied single-nucleus RNA sequencing and spatial transcriptomics to cortical...
Genetics
MS Risk Variants, Single Cell Expression, and MRI Brain Volume
02, Oct 2026This post covers Upcott and colleagues' 2026 medRxiv preprint, which builds cell-type specific transcriptional risk scores for MS by weighting...
Genetics
An MS Severity Variant Measured as Brain Atrophy
01, Oct 2026This post covers Gasperi and colleagues' 2023 Annals of Neurology brief communication, which tested whether the MS severity variant rs10191329 is...
Genetics
MS Genetic Risk, Healthy Brains, and an Effect Measured in Milliseconds
29, Sep 2026This post covers Feng and colleagues' 2026 study in Magnetic Resonance in Medical Sciences, which tested whether a polygenic risk score for...
Genetics
Genotype and the Periventricular Edge in MS
28, Sep 2026This post covers Sombekke and colleagues' 2011 AJNR exploratory study, which tested 69 candidate SNPs against voxelwise lesion probability in 208...
Genetics
Where MS Lesions Sit, Treated as a Genetic Trait
28, Sep 2026This post covers Gourraud and colleagues' 2013 Brain study, which turned the three-dimensional distribution of white matter lesions into a...
Genetics
Two Loci for How MS Progresses, Not Whether It Starts
23, Sep 2026This post covers Loomis and colleagues' 2023 Scientific Reports study, the first GWAS meta-analysis of longitudinal brain MRI measures of MS...