Genetics
What MS Genetics Predicts After Diagnosis07, Nov 2026
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Genetics
The Conditions an MS Risk Variant Needs
05, Nov 2026MS risk alleles are mostly conditional, registering only when the measurement carries the stimulus, compartment or resolution they depend on....
Genetics
Why MS Progression Has Its Own Gene List
05, Nov 2026Multiple sclerosis susceptibility genetics is nearly solved and almost entirely immune; progression genetics is barely started. Three 2026 papers...
Genetics
When MS Genetics Meets scRNA-seq
02, Nov 2026Three recent multiple sclerosis papers of the same kind, public datasets run through a statistical pipeline with single-cell or single-nucleus...
Genetics
Three Ways MS Genetics Studies Use Single-Cell Sequencing
01, Nov 2026Three recent MS genetics papers, compared by the job each gives to single-cell or single-nucleus RNA sequencing, since the direction of travel...
Genetics
Metabolism Off Reused Single-Cell Data in MS
30, Oct 2026This post looks at three recent MS studies that all read metabolism off single-cell data they largely did not generate, and compares how much...
Genetics
MS Risk Loci Through Single Cells
26, Oct 2026This post covers three papers that read MS genetic risk through single-cell data rather than bulk tissue. Fujimoto and colleagues report a...
Genetics
Where MS Risk Genes Act Inside the Brain
25, Oct 2026This post asks what MS susceptibility genes, almost all of which point at immune cells, are doing in neural tissue, and whether anyone can show it...
Genetics
Measuring Tissue in MS Genetics
24, Oct 2026This post keeps three things in every cited study at once: genotyping, a CNS tissue measurement rather than a disability score, and relevance to...
Genetics
MS Single-Cell Data by Perturbing It
22, Oct 2026This post covers four human studies from 2026 that read MS single-cell data through perturbation rather than description, with no animal model...
Genetics
Where the Vitamin D Benefit Stops in MS Risk
15, Oct 2026This post covers Yu and colleagues' 2024 Nutrition Journal study, which stacked four layers of evidence on vitamin D and MS: a prospective cohort...
Genetics
Which Metabolites Cause MS? The First Metabolome-Wide Mendelian Randomization Study in MS
12, Oct 2026This post covers Ge and colleagues' 2023 metabolome-wide Mendelian randomization study in the Journal of Neuroimmunology, which tested 571...
Genetics
More Enzyme, Less Branching, and More MS Risk
11, Oct 2026This post covers Mkhikian and colleagues' 2011 Nature Communications study, which inverted the usual order of genetic work by screening...